Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:17602
Term: 4-aminophenol
Definition: An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
Chemical ID: MESH:C026729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD4-aminophenol results in increased activity of and results in increased cleavage of CASP12 protein, 4-aminophenol results in increased cleavage of and results in increased activity of CASP12 protein, PD 150606 inhibits the reaction [4-aminophenol results in increased activity of and results in increased cleavage of CASP12 protein]

PMID:17567590, PMID:17567592
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.