GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp12 | increases activity | ISO | CASP12 (Homo sapiens) | 6480464 | CTD | Ethanol results in increased activity of CASP12 protein | PMID:24224909 | Casp12 | increases cleavage | ISO | Casp12 (Mus musculus) | 6480464 | CTD | Ethanol results in increased cleavage of CASP12 protein | PMID:28119953 | Casp12 | increases expression | ISO | CASP12 (Homo sapiens) | 6480464 | CTD | Ethanol results in increased expression of CASP12 protein modified form | PMID:24224909 | Casp12 | increases expression | ISO | Casp12 (Mus musculus) | 6480464 | CTD | Ethanol results in increased expression of CASP12 protein | PMID:27983966 | Casp12 | multiple interactions | ISO | CASP12 (Homo sapiens) | 6480464 | CTD | Resveratrol inhibits the reaction [Ethanol results in increased activity of CASP12 protein]; Resveratrol inhibits the reaction [Ethanol results in increased expression of CASP12 protein modified form] | PMID:24224909 | Casp12 | multiple interactions | ISO | Casp12 (Mus musculus) | 6480464 | CTD | Cimetidine inhibits the reaction [Ethanol results in increased expression of CASP12 protein]; Drugs, Chinese Herbal inhibits the reaction [Ethanol results in increased expression of CASP12 protein]; Hydralazine inhibits the reaction [Ethanol results in increased cleavage of CASP12 protein] | PMID:27983966 PMID:28119953 | | ||||||||||||||||||||||
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