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GENE - TERM ANNOTATION REPORT

RGD ID: 621737
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Flt4
Name: Fms related receptor tyrosine kinase 4
Acc ID: GO:0048010
Term: vascular endothelial growth factor receptor signaling pathway
Definition: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Flt4 IMP 727326RGD  
Flt4acts_upstream_of_or_withinISOFLT4 (Homo sapiens)1624291RGD PMID:9012504

PMID:9012504
Flt4involved_inISOFLT4 (Homo sapiens)1624291RGD PMID:11532940 PMID:19779139

PMID:11532940 PMID:19779139
Flt4involved_inIEAUniProtKB:P35916 or ensembl:ENSP000002619371600115EnsemblGO_REF:0000107

GO_REF:0000107
Flt4involved_inIBAPANTHER:PTN002814453 or Flt4 (Rattus norvegicus) or UniProtKB:P35916 or ZFIN:ZDB-GENE-980526-3261600115GO_CentralGO_REF:0000033

GO_REF:0000033
Flt4involved_inIEAPANTHER:PTHR24416:SF491600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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