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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit4increases expressionEXP 6480464CTDbisphenol A results in increased expression of DDIT4 mRNAPMID:25181051 PMID:30816183 PMID:32145629 PMID:32528016
Ddit4multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DDIT4 mRNAPMID:36041667
Ddit4increases expressionISODDIT4 (Homo sapiens)6480464CTDbisphenol A analog results in increased expression of DDIT4 mRNA; bisphenol A results in increased expression of DDIT4 mRNAPMID:29275510 PMID:29718440 PMID:32387340
Ddit4increases expressionISODdit4 (Mus musculus)6480464CTDbisphenol A results in increased expression of DDIT4 mRNAPMID:25270620 PMID:32156529
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