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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621724
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oat
Name: ornithine aminotransferase
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oataffects expressionEXP 6480464CTDCadmium Chloride affects the expression of OAT mRNAPMID:22110744
Oatdecreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of OAT mRNAPMID:25993096
Oatincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of OAT mRNAPMID:21297351
Oatdecreases expressionISOOAT (Homo sapiens)6480464CTDCadmium Chloride results in decreased expression of OAT proteinPMID:24527689
Oatincreases expressionISOOAT (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of OAT proteinPMID:24527689
Oatmultiple interactionsISOOAT (Homo sapiens)6480464CTD2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of OAT protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of OAT mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of OAT proteinPMID:35301059 PMID:38195004
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