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GENE - TERM ANNOTATION REPORT

RGD ID: 621700
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sftpb
Name: surfactant protein B
Acc ID: DOID:1273
Term: respiratory syncytial virus infectious disease
Definition: A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus, which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress. (DO)
Definition Source(s): http://www.merck.com/mmhe/sec23/ch273/ch273i.html?qt=respiratory%20syncytial%20virus&alt=sh#sec23-ch273-ch273i-982g "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sftpb ISOSFTPB (Homo sapiens)4143439RGDprotein:decreased expression:lung 
SftpbseverityISOSFTPB (Homo sapiens)4143382RGDDNA:SNPs:promoter, cds, intron:-32G>T (rs2077079), p.T131I (rs1130866), 5781A>C (rs2040349) (human) 
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