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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621678
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fads1
Name: fatty acid desaturase 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fads1affects expressionEXP 6480464CTDEstradiol affects the expression of FADS1 mRNAPMID:32145629
Fads1increases expressionISOFADS1 (Homo sapiens)6480464CTDEstradiol results in increased expression of FADS1 mRNAPMID:20106945
Fads1multiple interactionsISOFADS1 (Homo sapiens)6480464CTD[[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated; [alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA; fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA]PMID:19576517
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