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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621676
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acta2
Name: actin alpha 2, smooth muscle
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acta2multiple interactionsEXP 6480464CTDepigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]PMID:19646978
Acta2affects expressionISOActa2 (Mus musculus)6480464CTDepigallocatechin gallate affects the expression of ACTA2PMID:25955525
Acta2multiple interactionsISOActa2 (Mus musculus)6480464CTDepigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of ACTA2 protein]PMID:20438794 PMID:22101032
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