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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621647
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vip
Name: vasoactive intestinal peptide
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: A polyphenol that has formula C18H20O2.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDDiethylstilbestrol results in increased expression of VIP mRNA, Diethylstilbestrol results in increased expression of VIP protein

PMID:12960047, PMID:15677882, PMID:17005392
multiple interactionsEXP 6480464CTD[Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein], Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP mRNA], Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein], vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)- promotes the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]

PMID:15677882
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.