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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimaffects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of VIM mRNAPMID:12734012
Vimincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of VIM proteinPMID:12629582 PMID:30254303
Vimmultiple interactionsEXP 6480464CTDCarvedilol inhibits the reaction [Carbon Tetrachloride results in increased expression of VIM protein]PMID:30254303
Vimaffects expressionISOVim (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of VIM mRNAPMID:31919559
Vimincreases expressionISOVim (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of VIM mRNA; Carbon Tetrachloride results in increased expression of VIM proteinPMID:15056808 PMID:18038451 PMID:27339419 PMID:29987408 PMID:32659284
Vimmultiple interactionsISOVim (Mus musculus)6480464CTDMICAL2 mRNA promotes the reaction [Carbon Tetrachloride results in increased expression of VIM protein]; MIR203 mRNA inhibits the reaction [Carbon Tetrachloride results in increased expression of VIM protein]; PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of VIM mRNA]; SHC1 protein promotes the reaction [Carbon Tetrachloride results in increased expression of VIM protein]PMID:18038451 PMID:32659284
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