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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimincreases expressionEXP 6480464CTDEstradiol results in increased expression of VIM mRNAPMID:32145629
Vimincreases expressionISOVIM (Homo sapiens)6480464CTDEstradiol results in increased expression of VIM mRNA; Estradiol results in increased expression of VIM proteinPMID:25690688 PMID:26407941 PMID:35044086
Vimmultiple interactionsISOVIM (Homo sapiens)6480464CTD[Arsenic co-treated with Estradiol] results in decreased expression of VIM mRNA; [Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein; [Estradiol co-treated with Progesterone] results in decreased expression of VIM mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of VIM mRNA; AG 1879 inhibits the reaction [Estradiol results in increased expression of VIM protein]; ESR1 protein alternative form promotes the reaction [Estradiol results in increased expression of VIM protein]; Estradiol promotes the reaction [VIM protein binds to ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of VIM mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of VIM protein]; Genistein inhibits the reaction [Estradiol results in increased expression of VIM protein]PMID:20660070 PMID:20823114 PMID:25690688 PMID:26407941 PMID:27156127 PMID:30165855 PMID:33047385 PMID:35044086
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