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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM mRNA]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM protein]; Quercetin inhibits the reaction [Doxorubicin results in increased expression of VIM protein]PMID:25164625 PMID:29474904
Vimdecreases expressionISOVIM (Homo sapiens)6480464CTDQuercetin results in decreased expression of VIM mRNA; Quercetin results in decreased expression of VIM proteinPMID:22422628 PMID:33070227
Vimmultiple interactionsISOVIM (Homo sapiens)6480464CTDSHH protein inhibits the reaction [Quercetin results in decreased expression of VIM protein]PMID:33070227
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