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GENE - TERM ANNOTATION REPORT

RGD ID: 621641
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Soat1
Name: sterol O-acyltransferase 1
Acc ID: GO:0008203
Term: cholesterol metabolic process
Definition: The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Soat1acts_upstream_of_or_withinISOSOAT1 (Homo sapiens)1624291RGD PMID:9756919

PMID:9756919
Soat1acts_upstream_of_or_withinISOSoat1 (Mus musculus)1624291RGD PMID:15845870

PMID:15845870
Soat1involved_inISOSOAT1 (Homo sapiens)1624291RGD PMID:16647063 PMID:8407899

PMID:16647063 PMID:8407899
Soat1 TAS 730254RGD  
Soat1involved_inIEAUniProtKB:P35610 or ensembl:ENSP000003565911600115EnsemblGO_REF:0000107

GO_REF:0000107
Soat1involved_inIEAUniProtKB:Q61263 or ensembl:ENSMUSP000001407211600115EnsemblGO_REF:0000107

GO_REF:0000107
Soat1involved_inIBAMGI:104665 or MGI:1332226 or PANTHER:PTN000823452 or Soat2 (Rattus norvegicus) or UniProtKB:O75908 or UniProtKB:P356101600115GO_CentralGO_REF:0000033

GO_REF:0000033
Soat1involved_inISSUniProtKB:O777601600115UniProtGO_REF:0000024

GO_REF:0000024
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