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GENE - TERM ANNOTATION REPORT

RGD ID: 621619
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Keap1
Name: Kelch-like ECH-associated protein 1
Acc ID: GO:0031463
Term: Cul3-RING ubiquitin ligase complex
Definition: A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
Definition Source(s): PMID:15571813, PMID:15688063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Keap1part_ofISOKEAP1 (Homo sapiens)1624291RGD PMID:15601839 PMID:15983046

PMID:15601839 PMID:15983046
Keap1part_ofISOKeap1 (Mus musculus)1624291RGD MGI:6368080 PMID:15282312 MGI:6368086 PMID:15367669

MGI:6368080 MGI:6368086 PMID:15282312 PMID:15367669
Keap1part_ofIEAUniProtKB:Q14145 or ensembl:ENSP000001711111600115EnsemblGO_REF:0000107

GO_REF:0000107
Keap1part_ofIEAUniProtKB:Q9Z2X8 or ensembl:ENSMUSP000001310291600115EnsemblGO_REF:0000107

GO_REF:0000107
Keap1part_ofISSUniProtKB:Q141451600115UniProtGO_REF:0000024

GO_REF:0000024
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