GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | increases cleavage | EXP | | 6480464 | CTD | triptolide results in increased cleavage of CASP9 protein | PMID:32835833 | Casp9 | increases expression | EXP | | 6480464 | CTD | triptolide results in increased expression of CASP9 protein modified form | PMID:30009776 | Casp9 | multiple interactions | EXP | | 6480464 | CTD | triptolide results in increased expression of and results in increased activity of CASP9 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form] | PMID:26990902 PMID:30009776 | Casp9 | increases activity | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | triptolide results in increased activity of CASP9 protein | PMID:26277538 | Casp9 | increases expression | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | triptolide results in increased expression of CASP9 protein modified form | PMID:30009776 | Casp9 | multiple interactions | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | pifithrin inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP9 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form] | PMID:26277538 PMID:30009776 | | ||||||||||||||||||||||
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