GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | decreases activity | EXP | | 6480464 | CTD | Selenium results in decreased activity of CASP9 protein | PMID:17997286 | Casp9 | multiple interactions | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [arsenite results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] | PMID:21628957 PMID:29324385 PMID:34612572 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]]; [Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]; Selenium analog inhibits the reaction [Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] | PMID:17339365 PMID:27920530 PMID:34612572 | | ||||||||||||||||||||||
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