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GENE - TERM ANNOTATION REPORT

RGD ID: 621589
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gak
Name: cyclin G associated kinase
Acc ID: GO:0072318
Term: clathrin coat disassembly
Definition: The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.
Definition Source(s): PMID:11084334, PMID:11146663, PMID:8524399
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gakacts_upstream_of_or_withinISOGak (Mus musculus)1624291RGDMGI:105384 PMID:20160091

PMID:20160091
Gakinvolved_inISOGAK (Homo sapiens)1624291RGD PMID:16155256

PMID:16155256
Gakinvolved_inIEAUniProtKB:O14976 or ensembl:ENSP000003144991600115EnsemblGO_REF:0000107

GO_REF:0000107
Gakinvolved_inIBAMGI:1919935 or MGI:2442153 or PANTHER:PTN000571055 or SGD:S000002728 or UniProtKB:O14976 or UniProtKB:Q279741600115GO_CentralGO_REF:0000033

GO_REF:0000033
Gakinvolved_inIEAPANTHER:PTHR23172:SF341600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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