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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621575
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vdac1
Name: voltage-dependent anion channel 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdac1increases expressionISOVdac1 (Mus musculus)6480464CTDOxygen deficiency results in increased expression of VDAC1 protein; Oxygen results in increased expression of VDAC1 proteinPMID:25937538 PMID:30529165
Vdac1multiple interactionsISOVdac1 (Mus musculus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of VDAC1 protein; NFE2L2 protein affects the reaction [Oxygen results in increased expression of VDAC1 protein]; NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of VDAC1 protein]]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of VDAC1 protein]; sulforaphane promotes the reaction [Oxygen results in increased expression of VDAC1 protein]; VDAC1 protein inhibits the reaction [Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; VDAC1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; VDAC1 protein results in increased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]PMID:25488258 PMID:30529165
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