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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621506
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk8
Name: mitogen-activated protein kinase 8
Acc ID: CHEBI:36904
Term: elemental selenium
Definition: null
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk8decreases expressionISOMapk8 (Mus musculus)6480464CTDSelenium results in decreased expression of MAPK8 mRNAPMID:28810182
Mapk8decreases phosphorylationISOMapk8 (Mus musculus)6480464CTDSelenium results in decreased phosphorylation of MAPK8 proteinPMID:17997286
Mapk8multiple interactionsISOMAPK8 (Homo sapiens)6480464CTDSelenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]PMID:26187450
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