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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621504
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnq2
Name: potassium voltage-gated channel subfamily Q member 2
Acc ID: CHEBI:18295
Term: histamine
Definition: A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.
Chemical ID: MESH:D006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnq2multiple interactionsISOKCNQ2 (Homo sapiens)6480464CTDAstemizole inhibits the reaction [Histamine results in decreased activity of [KCNQ2 protein co-treated with KCNQ3 protein co-treated with HRH1 protein]]; Histamine results in decreased activity of [KCNQ2 protein co-treated with KCNQ3 protein co-treated with HRH1 protein]PMID:12147327
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