Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 621420
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nbn
Name: nibrin
Acc ID: GO:0030870
Term: Mre11 complex
Definition: Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.
Definition Source(s): GOC:mah, GOC:vw, PMID:11988766, PMID:17674145
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAPANTHER:PTN000255549, PomBase:SPBC6B1.09c, UniProtKB:O6093413792537GO_CentralPMID:21873635

 
 IEAUniProtKB:O60934, ensembl:ENSP000002654331600115EnsemblGO_REF:0000107

GO_REF:0000107
 ISORGD:13486111624291RGD (PMID:19151086), (PMID:9590181)

PMID:19151086, PMID:9590181
 ISSUniProtKB:O609341600115UniProtGO_REF:0000024

GO_REF:0000024
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.