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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:35509
Term: androstane
Definition: A steroid fundamental parent that has formula C19H32.
Chemical ID: MESH:D000732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3multiple interactionsISONR1I3 (Homo sapiens)6480464CTD[Dibutyl Phthalate co-treated with Androstanols] results in increased activity of NR1I3 protein alternative form; [diisobutyl phthalate co-treated with Androstanols] results in increased activity of NR1I3 protein alternative form; Androstanols binds to and results in decreased activity of NR1I3 protein; Androstanols binds to and results in increased activity of NR1I3 protein alternative formPMID:16054614 PMID:20869355 PMID:21227907
Nr1i3multiple interactionsISONr1i3 (Mus musculus)6480464CTDAndrostanols inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of NR1I3 mRNA]PMID:12807759
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