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GENE - TERM ANNOTATION REPORT

RGD ID: 621351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a2
Name: collagen type I alpha 2 chain
Acc ID: DOID:11476
Term: osteoporosis
Definition: A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Osteoporosis "DO" "DO", http://www.mayoclinic.com/health/osteoporosis/DS00128 "DO" "DO", http://www.niams.nih.gov/Health_Info/Bone/default.asp "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000360.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a2 ISOCOL1A2 (Homo sapiens)7240710OMIM  
Col1a2 ISOCOL1A2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism 
Col1a2 ISOCOL1A2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: OSTEOPOROSIS, INVOLUTIONAL | ClinVar Annotator: match by term: OsteoporosisPMID:15172002 PMID:16705691 PMID:16786509 PMID:17078022 PMID:18028452 PMID:19344236 PMID:1978725 PMID:21520333 PMID:22589248 PMID:25326637 PMID:25450603 PMID:25741868 PMID:25944380 PMID:26264438 PMID:26307460 PMID:26371943 PMID:26432670 PMID:26467025 PMID:26604951 PMID:27011056 PMID:27519266 PMID:28017821 PMID:28492532 PMID:29150909 PMID:2985635 PMID:30283887 PMID:30821104 PMID:32659730 PMID:7695699 PMID:7860070 PMID:8094076 PMID:8218237 PMID:9016532 PMID:9272740 PMID:9399846 PMID:9594376 PMID:9923651
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