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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:34778
Term: glycitein
Definition: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.
Chemical ID: MESH:C086566
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9decreases expressionISOMMP9 (Homo sapiens)6480464CTDglycitein results in decreased expression of MMP9 mRNA; glycitein results in decreased expression of MMP9 proteinPMID:20188714
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDglycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]PMID:20188714
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