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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp2decreases activityISOMMP2 (Homo sapiens)6480464CTDtroglitazone results in decreased activity of MMP2 proteinPMID:18155510
Mmp2increases expressionISOMmp2 (Mus musculus)6480464CTDtroglitazone results in increased expression of MMP2 mRNAPMID:28973697
Mmp2multiple interactionsISOMMP2 (Homo sapiens)6480464CTDtroglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]PMID:18155510
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