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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp2multiple interactionsISOMMP2 (Homo sapiens)6480464CTDDecitabine inhibits the reaction [monomethylarsonous acid results in decreased expression of MMP2 mRNA]; Decitabine inhibits the reaction [sodium arsenite results in increased expression of MMP2 mRNA]; Decitabine inhibits the reaction [sodium arsenite results in increased expression of MMP2 protein]PMID:16507463 PMID:21167264
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