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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621315
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map1lc3b
Name: microtubule-associated protein 1 light chain 3 beta
Acc ID: CHEBI:37659
Term: oleanolic acid
Definition: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.
Chemical ID: MESH:D009828
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map1lc3bincreases expressionISOMAP1LC3B (Homo sapiens)6480464CTDOleanolic Acid results in increased expression of MAP1LC3B proteinPMID:31306688
Map1lc3bmultiple interactionsISOMAP1LC3B (Homo sapiens)6480464CTDCisplatin promotes the reaction [Oleanolic Acid results in increased expression of MAP1LC3B protein]; Oleanolic Acid promotes the reaction [Cisplatin results in increased expression of MAP1LC3B protein]; Oleanolic Acid results in increased expression of and results in increased lipidation of MAP1LC3B proteinPMID:31306688 PMID:35690101
Map1lc3bmultiple interactionsISOMap1lc3b (Mus musculus)6480464CTDOleanolic Acid inhibits the reaction [Cisplatin results in increased expression of MAP1LC3B protein]PMID:31306688
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