GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mt3 | increases expression | EXP | | 6480464 | CTD | Copper deficiency results in increased expression of MT3 mRNA; Copper results in increased expression of MT3 mRNA | PMID:26033743 PMID:30556269 | Mt3 | affects binding | ISO | MT3 (Homo sapiens) | 6480464 | CTD | Copper binds to [MT3 protein binds to Zinc]; Copper binds to MT3 protein; MT3 protein binds to Copper | PMID:12072966 PMID:12911326 PMID:15461142 PMID:15755312 PMID:15782327 PMID:17389590 PMID:36918407 | Mt3 | multiple interactions | ISO | MT3 (Homo sapiens) | 6480464 | CTD | [[MT3 protein binds to Zinc] which co-treated with Ascorbic Acid] inhibits the reaction [Copper results in increased chemical synthesis of Hydroxyl Radical]; [[MT3 protein binds to Zinc] which results in increased reduction of Copper] promotes the reaction [Copper binds to [MT3 protein binds to Zinc]]; [Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA; [MT3 protein binds to Zinc] which results in increased reduction of Copper | PMID:17389590 PMID:24690739 | | ||||||||||||||||||||||
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