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GENE - TERM ANNOTATION REPORT

RGD ID: 621242
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Acc ID: GO:0004222
Term: metalloendopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adamts4enablesISOAdamts4 (Mus musculus)1624291RGD PMID:23684986

PMID:23684986
Adamts4enablesIBAMGI:109249 or MGI:1339949 or MGI:2660628 or PANTHER:PTN000347317 or UniProtKB:P58397 or UniProtKB:Q76LX8 or UniProtKB:Q9UHI8 or UniProtKB:Q9UKP4 or UniProtKB:Q9UNA01600115GO_CentralGO_REF:0000033

GO_REF:0000033
Adamts4enablesIBAMGI:109249 or MGI:1339949 or MGI:2660628 or PANTHER:PTN000347317 or UniProtKB:P58397 or UniProtKB:Q9UHI8 or UniProtKB:Q9UKP4 or UniProtKB:Q9UNA01600115GO_CentralGO_REF:0000033

GO_REF:0000033
Adamts4enablesIEAInterPro:IPR0015901600115InterProGO_REF:0000002

GO_REF:0000002
Adamts4enablesIEAPANTHER:PTHR13723:SF381600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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