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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621177
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scd2
Name: stearoyl-Coenzyme A desaturase 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scd2increases expressionEXP 6480464CTDpirinixic acid results in increased expression of SCD2 mRNA

PMID:19162173
Scd2affects expressionISORGD:13318676480464CTDpirinixic acid affects the expression of SCD2 mRNA

PMID:19136022
Scd2increases expressionISORGD:13318676480464CTDpirinixic acid results in increased expression of SCD2 mRNA

PMID:17426115, PMID:17950772, PMID:19772884, PMID:23811191
Scd2multiple interactionsISORGD:13318676480464CTDACAA1B protein inhibits the reaction [pirinixic acid results in increased expression of SCD2 mRNA], PPARA protein promotes the reaction [pirinixic acid results in increased expression of SCD2 mRNA]

PMID:17950772, PMID:19772884
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.