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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621172
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa6
Name: annexin A6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa6increases expressionEXP 6480464CTDbisphenol A results in increased expression of ANXA6 mRNAPMID:25181051
Anxa6affects expressionISOANXA6 (Homo sapiens)6480464CTDbisphenol A affects the expression of ANXA6 mRNAPMID:30903817
Anxa6decreases expressionISOANXA6 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of ANXA6 proteinPMID:31675489 PMID:32981897 PMID:33376534 PMID:34186270
Anxa6increases expressionISOANXA6 (Homo sapiens)6480464CTDbisphenol A results in increased expression of ANXA6 proteinPMID:37567409
Anxa6increases expressionISOAnxa6 (Mus musculus)6480464CTDbisphenol A results in increased expression of ANXA6 mRNA; bisphenol A results in increased expression of ANXA6 proteinPMID:28279065 PMID:30951980
Anxa6multiple interactionsISOANXA6 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANXA6 mRNAPMID:28628672
Anxa6multiple interactionsISOAnxa6 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ANXA6 mRNAPMID:30951980
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