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GENE - TERM ANNOTATION REPORT

RGD ID: 621159
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1rn
Name: interleukin 1 receptor antagonist
Acc ID: DOID:9001109
Term: Anorexia
Definition: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
Definition Source(s): MESH:D000855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1rn IEP 8551744RGDassociated with Adenocarcinoma;mRNA:increased expression:cerebral cortex, hypothalamus (rat) 
Il1rn ISOIL1RN (Homo sapiens)11554173CTDCTD Direct Evidence: therapeuticPMID:25392278
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