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GENE - TERM ANNOTATION REPORT

RGD ID: 621159
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1rn
Name: interleukin 1 receptor antagonist
Acc ID: DOID:9002211
Term: Hyperalgesia
Definition: An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
Definition Source(s): MESH:D006930
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1rn IDA 6909165RGD  
Il1rnseverityIMP 8549800RGD  
Il1rn ISOIL1RN (Homo sapiens)6909175RGDassociated with Arthritis, Experimental; rat model treated with human protein 
Il1rntreatmentISOIL1RN (Homo sapiens)7401210RGD  
Il1rn ISOIL1RN (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:8864563 PMID:15317861 PMID:17174526 PMID:20937348
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