GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1rn | increases expression | EXP | | 6480464 | CTD | pirinixic acid results in increased expression of IL1RN mRNA | PMID:19162173 | Il1rn | increases expression | ISO | Il1rn (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of IL1RN mRNA; pirinixic acid results in increased expression of IL1RN protein | PMID:17321000 PMID:18301758 PMID:20059764 PMID:20813756 PMID:23811191 | Il1rn | multiple interactions | ISO | IL1RN (Homo sapiens) | 6480464 | CTD | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of IL1RN mRNA | PMID:19710929 | Il1rn | multiple interactions | ISO | Il1rn (Mus musculus) | 6480464 | CTD | [pirinixic acid co-treated with PPARA] results in increased expression of IL1RN mRNA; pirinixic acid promotes the reaction [[PPARA protein co-treated with RXRA protein] results in increased expression of IL1RN mRNA]; pirinixic acid promotes the reaction [PPARA protein binds to IL1RN protein]; PPARA protein affects the reaction [pirinixic acid results in increased expression of IL1RN mRNA]; PPARA protein affects the reaction [pirinixic acid results in increased expression of IL1RN protein]; PPARA protein promotes the reaction [pirinixic acid results in increased expression of IL1RN mRNA] | PMID:17321000 PMID:20059764 PMID:20813756 | | ||||||||||||||||||||||
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