GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk6 | affects response to substance | ISO | CDK6 (Homo sapiens) | 6480464 | CTD | CDK6 affects the susceptibility to fulvestrant | PMID:24169358 | Cdk6 | increases expression | ISO | CDK6 (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased expression of CDK6 protein | PMID:24169358 | Cdk6 | multiple interactions | ISO | CDK6 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CDK6 gene; [CDK6 affects the susceptibility to Fulvestrant] which affects the expression of CCNA1 protein; [CDK6 affects the susceptibility to Fulvestrant] which affects the phosphorylation of RB1 protein | PMID:24169358 PMID:31601247 | |
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