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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sfrp1
Name: secreted frizzled-related protein 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sfrp1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SFRP1 mRNAPMID:34747641
Sfrp1affects expressionISOSfrp1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SFRP1 mRNAPMID:21570461
Sfrp1decreases expressionISOSfrp1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SFRP1 mRNAPMID:19759094 PMID:33956508
Sfrp1multiple interactionsISOSfrp1 (Mus musculus)6480464CTDAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of SFRP1 mRNA]PMID:19759094
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