GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Csf2 | decreases expression | ISO | CSF2 (Homo sapiens) | 6480464 | CTD | Dexamethasone results in decreased expression of CSF2 mRNA | PMID:10596698 | Csf2 | increases activity | ISO | CSF2 (Homo sapiens) | 6480464 | CTD | Dexamethasone results in increased activity of CSF2 protein | PMID:11730731 | Csf2 | multiple interactions | ISO | CSF2 (Homo sapiens) | 6480464 | CTD | [Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; [trichostatin A co-treated with Dexamethasone] inhibits the reaction [IL1B protein promotes the reaction [H4C16 protein modified form binds to CSF2 promoter]]; Dexamethasone inhibits the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CSF2 protein]; Dexamethasone inhibits the reaction [IL13 protein results in increased secretion of CSF2 protein]; Dexamethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Dexamethasone inhibits the reaction [IL4 protein results in increased secretion of CSF2 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 protein]; Dexamethasone inhibits the reaction [lipoteichoic acid results in increased secretion of CSF2 protein]; Dexamethasone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]; Dexamethasone inhibits the reaction [TNF protein results in increased secretion of CSF2 protein]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]]; trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]]; trichostatin A inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] | PMID:12070353 PMID:12077271 PMID:14998300 PMID:16908450 PMID:19255438 PMID:20801891 PMID:23981542 PMID:27568862 | Csf2 | multiple interactions | ISO | Csf2 (Mus musculus) | 6480464 | CTD | Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 protein] | PMID:16880258 PMID:27568862 | |
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