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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620969
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map3k8
Name: mitogen-activated protein kinase kinase kinase 8
Acc ID: CHEBI:81068
Term: Shikonin
Definition: A hydroxy-1,4-naphthoquinone that has formula C16H16O5.
Chemical ID: MESH:C016101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k8multiple interactionsISOMap3k8 (Mus musculus)6480464CTDshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of MAP3K8 mRNA]; shikonin inhibits the reaction [Calcimycin results in increased expression of MAP3K8 mRNA]PMID:25451590
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