GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp7 | increases expression | ISO | CASP7 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of CASP7 mRNA | PMID:15894607 PMID:16166294 PMID:33167477 PMID:34742744 | Casp7 | multiple interactions | ISO | CASP7 (Homo sapiens) | 6480464 | CTD | [Tretinoin co-treated with zoledronic acid] results in increased activity of CASP7 protein; CRABP2 protein promotes the reaction [Tretinoin results in increased cleavage of and results in increased activity of CASP7 protein]; Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]; Tretinoin results in increased cleavage of and results in increased activity of CASP7 protein | PMID:16166294 PMID:20349282 | Casp7 | multiple interactions | ISO | Casp7 (Mus musculus) | 6480464 | CTD | Tretinoin promotes the reaction [arsenic trioxide results in increased cleavage of CASP7 protein] | PMID:15688020 | | ||||||||||||||||||||||
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