GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ppargc1a | increases expression | EXP | | 6480464 | CTD | Palmitic Acid results in increased expression of PPARGC1A mRNA | PMID:23056435 | Ppargc1a | decreases expression | ISO | Ppargc1a (Mus musculus) | 6480464 | CTD | Palmitic Acid results in decreased expression of PPARGC1A mRNA; Palmitic Acid results in decreased expression of PPARGC1A protein | PMID:34485530 | Ppargc1a | increases expression | ISO | PPARGC1A (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in increased expression of PPARGC1A mRNA | PMID:23056435 | Ppargc1a | multiple interactions | ISO | Ppargc1a (Mus musculus) | 6480464 | CTD | [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of PPARGC1A mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of PPARGC1A protein] | PMID:26847930 PMID:34485530 | Ppargc1a | multiple interactions | ISO | PPARGC1A (Homo sapiens) | 6480464 | CTD | [Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] | PMID:32730863 | | ||||||||||||||||||||||
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