GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsf1 | increases phosphorylation | EXP | | 6480464 | CTD | arsenite results in increased phosphorylation of HSF1 protein | PMID:9764755 | Hsf1 | multiple interactions | EXP | | 6480464 | CTD | [arsenite co-treated with Curcumin] results in increased phosphorylation of HSF1 protein | PMID:9764755 | Hsf1 | affects localization | ISO | Hsf1 (Mus musculus) | 6480464 | CTD | arsenite affects the localization of HSF1 protein | PMID:20835880 | Hsf1 | increases activity | ISO | Hsf1 (Mus musculus) | 6480464 | CTD | arsenite results in increased activity of HSF1 protein | PMID:20835880 | Hsf1 | increases expression | ISO | Hsf1 (Mus musculus) | 6480464 | CTD | arsenite results in increased expression of HSF1 protein | PMID:20835880 | Hsf1 | multiple interactions | ISO | Hsf1 (Mus musculus) | 6480464 | CTD | HSF1 protein affects the reaction [arsenite results in increased expression of HSPA1B mRNA]; HSF1 protein affects the reaction [arsenite results in increased expression of HSPA1B protein]; PIK3R1 gene mutant form inhibits the reaction [arsenite affects the localization of HSF1 protein]; PIK3R1 gene mutant form inhibits the reaction [arsenite results in increased expression of HSF1 protein] | PMID:20835880 | | ||||||||||||||||||||||
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