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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62089
Species: Mus musculus
RGD Object: Gene
Symbol: Prkn
Name: parkin RBR E3 ubiquitin protein ligase
Acc ID: CHEBI:9607
Term: Tiron
Definition: An organic molecular entity that has formula C6H4O8S2.2Na.
Chemical ID: MESH:D014013
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prknmultiple interactionsEXP 6480464CTD1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]PMID:22872702
Prknmultiple interactionsISOPrkn (Rattus norvegicus)6480464CTD1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN protein]PMID:25787151
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