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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lif
Name: LIF, interleukin 6 family cytokine
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lifincreases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of LIF mRNAPMID:23630614 PMID:33354967
Lifaffects expressionISOLIF (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of LIF proteinPMID:20106945
Lifincreases expressionISOLIF (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of LIF mRNAPMID:21641981 PMID:22100608 PMID:27153756 PMID:32234424 PMID:35690182
Lifincreases expressionISOLif (Mus musculus)6480464CTDAflatoxin B1 results in increased expression of LIF mRNAPMID:19770486
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