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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620824
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Polr1a
Name: RNA polymerase I subunit A
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Polr1amultiple interactionsISOPolr1a (Mus musculus)6480464CTD[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of POLR1A mRNAPMID:25510870
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