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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620715
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnma1
Name: potassium calcium-activated channel subfamily M alpha 1
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnma1multiple interactionsISOKCNMA1 (Homo sapiens)6480464CTDGlucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]; Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; NS 1619 inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; Tamoxifen inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tetraethylammonium promotes the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]PMID:21413024
Kcnma1multiple interactionsISOKcnma1 (Mus musculus)6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KCNMA1 mRNAPMID:37567420
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