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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620690
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc2
Name: baculoviral IAP repeat-containing 2
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc2decreases expressionISOBIRC2 (Homo sapiens)6480464CTDresveratrol results in decreased expression of BIRC2 proteinPMID:11577002 PMID:25550561 PMID:26911335
Birc2increases expressionISOBIRC2 (Homo sapiens)6480464CTDresveratrol results in increased expression of BIRC2 mRNAPMID:12569576
Birc2multiple interactionsISOBIRC2 (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in increased expression of BIRC2 mRNA; BCL2 protein inhibits the reaction [Resveratrol results in decreased expression of BIRC2 protein]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of BIRC2 protein]PMID:11577002 PMID:23452621 PMID:23557933
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