GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fasn | decreases expression | ISO | Fasn (Mus musculus) | 6480464 | CTD | Protein Kinase Inhibitors results in decreased expression of FASN protein | PMID:26670611 | Fasn | multiple interactions | ISO | FASN (Homo sapiens) | 6480464 | CTD | mirdametinib inhibits the reaction [Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 protein]]; Protein Kinase Inhibitors inhibits the reaction [FASN protein affects the localization of ARRB1 protein]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Fatty Acids, Nonesterified]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Triglycerides]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of ACACA mRNA]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of ADIPOQ mRNA]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of FASN protein]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of RETN mRNA]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 mRNA]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 protein] | PMID:26670611 | | ||||||||||||||||||||||
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