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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620665
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fasn
Name: fatty acid synthase
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasndecreases expressionEXP 6480464CTDClofibrate results in decreased expression of FASN mRNA; Clofibrate results in decreased expression of FASN proteinPMID:17522070 PMID:19224547 PMID:8240402
Fasnincreases expressionEXP 6480464CTDClofibrate results in increased expression of FASN proteinPMID:6821269
Fasndecreases expressionISOFasn (Mus musculus)6480464CTDClofibrate results in decreased expression of FASN mRNAPMID:17585979 PMID:23811191
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