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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620665
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fasn
Name: fatty acid synthase
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasnincreases expressionEXP 6480464CTDSodium Glutamate results in increased expression of FASN mRNAPMID:26092479
Fasnincreases expressionISOFasn (Mus musculus)6480464CTDSodium Glutamate results in increased expression of FASN mRNA; Sodium Glutamate results in increased expression of FASN proteinPMID:19724016 PMID:32103741
Fasnmultiple interactionsISOFasn (Mus musculus)6480464CTD[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FASN mRNA; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of FASN protein]PMID:19001666 PMID:19724016 PMID:32103741
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