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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620608
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cox5b
Name: cytochrome c oxidase subunit 5B
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cox5bdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of COX5B mRNAPMID:34747641
Cox5bincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of COX5B mRNAPMID:33387578
Cox5baffects expressionISOCox5b (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of COX5B mRNAPMID:21570461
Cox5bdecreases expressionISOCox5b (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of COX5B mRNAPMID:21354282
Cox5bincreases expressionISOCox5b (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of COX5B mRNAPMID:17942748 PMID:20399798 PMID:28922406
Cox5bmultiple interactionsISOCox5b (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COX5B mRNAPMID:17942748
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